Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pou4f1  POU domain, class 4, transcription factor 1   (Synonyms: Brn3, Brn-3, Brn-3.0, Brn3a, E130119J07Rik)
Results	Reference
1*	J:214045 Audouard E, Schakman O, Ginion A, Bertrand L, Gailly P, Clotman F, The Onecut transcription factor HNF-6 contributes to proper reorganization of Purkinje cells during postnatal cerebellum development. Mol Cell Neurosci. 2013 Sep;56:159-68
1	J:294509 Bertacchi M, Gruart A, Kaimakis P, Allet C, Serra L, Giacobini P, Delgado-Garcia JM, Bovolenta P, Studer M, Mouse Nr2f1 haploinsufficiency unveils new pathological mechanisms of a human optic atrophy syndrome. EMBO Mol Med. 2019 Aug;11(8):e10291
1	J:175804 Brzezinski JA 4th, Kim EJ, Johnson JE, Reh TA, Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina. Development. 2011 Aug;138(16):3519-31
1	J:180432 D'Autreaux F, Coppola E, Hirsch MR, Birchmeier C, Brunet JF, Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20018-23
1	J:95327 de Melo J, Du G, Fonseca M, Gillespie LA, Turk WJ, Rubenstein JL, Eisenstat DD, Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina. Development. 2005 Jan;132(2):311-22
1	J:260552 Donnelly CR, Shah AA, Mistretta CM, Bradley RM, Pierchala BA, Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E516-E525
1	J:210692 Hagglund AC, Berghard A, Carlsson L, Canonical Wnt/beta-catenin signalling is essential for optic cup formation. PLoS One. 2013;8(12):e81158
1	J:162323 Inoue T, Kagawa T, Inoue-Mochita M, Isono K, Ohtsu N, Nobuhisa I, Fukushima M, Tanihara H, Taga T, Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis. FEBS Lett. 2010 Jul 16;584(14):3233-8
1	J:326949 Kirjavainen A, Singh P, Lahti L, Seja P, Lelkes Z, Makkonen A, Kilpinen S, Ono Y, Salminen M, Aitta-Aho T, Stenberg T, Molchanova S, Achim K, Partanen J, Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons. Development. 2022 Jul 15;149(14):dev200937
1	J:254469 Li J, Wang S, Anderson C, Zhao F, Qin Y, Wu D, Wu X, Liu J, He X, Zhao J, Zhang J, Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. PLoS One. 2016;11(8):e0159639
1	J:293412 Lipiec MA, Bem J, Kozinski K, Chakraborty C, Urban-Ciecko J, Zajkowski T, Dabrowski M, Szewczyk LM, Toval A, Ferran JL, Nagalski A, Wisniewska MB, TCF7L2 regulates postmitotic differentiation programmes and excitability patterns in the thalamus. Development. 2020 Aug 25;147(16):dev190181
1	J:205743 Liu H, Kim SY, Fu Y, Wu X, Ng L, Swaroop A, Forrest D, An isoform of retinoid-related orphan receptor beta directs differentiation of retinal amacrine and horizontal interneurons. Nat Commun. 2013;4:1813
1	J:298398 Liu J, Liu Y, Shao J, Li Y, Qin L, Shen H, Xie Y, Xia W, Gao WQ, Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex. Cell Death Differ. 2019 Nov;26(11):2479-2492
1	J:143462 Liu Z, Li H, Hu X, Yu L, Liu H, Han R, Colella R, Mower GD, Chen Y, Qiu M, Control of precerebellar neuron development by Olig3 bHLH transcription factor. J Neurosci. 2008 Oct 1;28(40):10124-33
1	J:160876 Ma L, Cantrup R, Varrault A, Colak D, Klenin N, Gotz M, McFarlane S, Journot L, Schuurmans C, Zac1 functions through TGFbetaII to negatively regulate cell number in the developing retina. Neural Dev. 2007;2:11
1	J:137605 Manuel M, Pratt T, Liu M, Jeffery G, Price DJ, Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59
1	J:261834 Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS, Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart. Cell Death Dis. 2017 Jun 8;8(6):e2861
1*	J:170258 Mavromatakis YE, Lin W, Metzakopian E, Ferri AL, Yan CH, Sasaki H, Whisett J, Ang SL, Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity. Mech Dev. 2011 Jan-Feb;128(1-2):90-103
1	J:310179 Moreno-Bravo JA, Perez-Balaguer A, Martinez-Lopez JE, Aroca P, Puelles L, Martinez S, Puelles E, Role of Shh in the development of molecularly characterized tegmental nuclei in mouse rhombomere 1. Brain Struct Funct. 2014 May;219(3):777-92
1	J:340810 Nishida K, Matsumura S, Uchida H, Abe M, Sakimura K, Badea TC, Kobayashi T, Brn3a controls the soma localization and axonal extension patterns of developing spinal dorsal horn neurons. PLoS One. 2023;18(9):e0285295
1	J:335863 Oda M, Yamamoto H, Matsumoto H, Ishizaki Y, Shibasaki K, TRPC5 regulates axonal outgrowth in developing retinal ganglion cells. Lab Invest. 2020 Feb;100(2):297-310
1	J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41
1*	J:149237 Perez-Balaguer A, Puelles E, Wurst W, Martinez S, Shh dependent and independent maintenance of basal midbrain. Mech Dev. 2009 May-Jun;126(5-6):301-13
1	J:152847 Prakash N, Puelles E, Freude K, Trumbach D, Omodei D, Di Salvio M, Sussel L, Ericson J, Sander M, Simeone A, Wurst W, Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain. Development. 2009 Aug;136(15):2545-55
1	J:271110 Ruiz-Reig N, Rakotobe M, Bethus I, Le Menn G, Huditz HI, Marie H, Lamonerie T, D'Autreaux F, Developmental Requirement of Homeoprotein Otx2 for Specific Habenulo-Interpeduncular Subcircuits. J Neurosci. 2019 Feb 6;39(6):1005-1019
1*	J:115166 Shibasaki K, Takebayashi H, Ikenaka K, Feng L, Gan L, Expression of the basic helix-loop-factor Olig2 in the developing retina: Olig2 as a new marker for retinal progenitors and late-born cells. Gene Expr Patterns. 2007 Jan;7(1-2):57-65
1	J:143526 Storm R, Cholewa-Waclaw J, Reuter K, Brohl D, Sieber M, Treier M, Muller T, Birchmeier C, The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei. Development. 2009 Jan;136(2):295-305
1	J:197145 Stott SR, Metzakopian E, Lin W, Kaestner KH, Hen R, Ang SL, Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages. J Neurosci. 2013 May 1;33(18):8022-34
1	J:75445 Wagner KD, Wagner N, Vidal VP, Schley G, Wilhelm D, Schedl A, Englert C, Scholz H, The Wilms' tumor gene Wt1 is required for normal development of the retina. EMBO J. 2002 Mar 15;21(6):1398-405
1*	J:97217 Wagner N, Wagner KD, Hammes A, Kirschner KM, Vidal VP, Schedl A, Scholz H, A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system. Development. 2005 Mar;132(6):1327-36
1	J:167837 Waite MR, Skidmore JM, Billi AC, Martin JF, Martin DM, GABAergic and glutamatergic identities of developing midbrain Pitx2 neurons. Dev Dyn. 2011 Feb;240(2):333-46
1	J:203656 Waite MR, Skidmore JM, Micucci JA, Shiratori H, Hamada H, Martin JF, Martin DM, Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development. Mol Cell Neurosci. 2013 Jan;52:128-39
1*	J:107704 Xiang M, Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev Biol. 1998 May 15;197(2):155-69
1	J:251744 Zega K, Jovanovic VM, Vitic Z, Niedzielska M, Knaapi L, Jukic MM, Partanen J, Friedel RF, Lang R, Brodski C, Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool. Front Mol Neurosci. 2017;10:372
1	J:241572 Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD, Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017 May 01;144(9):1698-1711